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The group uses a multidisciplinary approach at the interface of natural product research, mass spectrometry-based metabolomics, and proteomics as well as chemical biology www. The lab's science mission is to develop and apply mass spectrometry-based tools to systematically determine the role of small molecules in complex microbial communities and to mine them for novel bioactive compounds. Besides supportive mentoring and guidance for your individual career development, we provide detailed scientific training on state-of-the-art equipment and open, community-focused science communication.

A GTPase-induced switch in phospholipid affinity of collybistin contributes to synaptic gephyrin clustering. J Cell Sci. Jurek B, Chayka M, Kreye J, Lang K, Kraus L, Fidzinski P, Kornau HC, Dao LM, Wenke NK, Long M, Rivalan M, Winter Y, Leubner J, Herken J, Mayer Vorgesetzten flirten, Mueller S, Boehm-Sturm P, Dirnagl U, Schmitz D, Kölch M, Prüss H.

Human gestational NMDAR autoantibodies impair neonatal murine brain function.

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Ann Neurol. Neuronal vulnerability and multilineage diversity in multiple sclerosis. Immature excitatory neurons develop during adolescence in the human amygdala.

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Nat Commun, Jun 21;10 1 Velmeshev Frau maier single cluster, Schirmer L, Jung D, Haeussler M, Perez Y, Mayer S, Bhaduri A, Goyal N, Rowitch DH, Kriegstein AR. Single-Cell Genomics Identifies Cell Type-Specific Molecular Changes in Autism. Science, May 17; Multimodal single-cell analysis reveals physiological maturation in the developing human neocortex.

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Neuron, Apr 3; 1 Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults. Nature, Mar 15; Mayer S, Kumar R, Jaiswal M, Soykan T, Ahmadian MR, Brose N, Betz H, Rhee JS, Papadopoulos T.

Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission.

Automatic Intraoperative Tracking for Workflow and Dose Monitoring in X-Ray-based Minimally Invasive Surgeries Third Party Funds Single Term: June 1, - May 31, Funding source: Bundesministerium für Bildung und Forschung BMBF Abstract The goal of this project is the investigation of multimodal methods for the evaluation of interventional workflows in the operation room. This topic will be researched in an international project context with partners in Germany and in Brazil UNISINOS in Porto Alegre.

Proc Natl Acad Sci U S A. Spatiotemporal transcriptome of the human brain. Nature Oct 26; Übersichtsartikel Sarieva K, Mayer S. The Effects of Environmental Adversities on Human Neocortical Neurogenesis Modeled in Brain Organoids.

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Front Mol Biosci. Khakipoor S, Crouch EE, Mayer S. Human organoids to model the developing human neocortex in health and disease.

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Brain Res. Khakipoor S, Drömer MA, Cozetto DA, Mayer S. Single-cell RNA-Sequencing in Neuroscience. Does Adult Neurogenesis Persist in the Human Hippocampus? Cell Stem Cell, Dec 6;23 6 Mayer S, Kriegstein AR.

The expansion of the cortical sheet in primates.

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In: Kaas, J ed. Oxford: Elsevier.

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